PDE6B and retinitis pigmentosa 1: Conclusively, the decrease in all parameters that was noted in Fam161atm1b/tm1b mice during the period of the experiment, showed both that the functional and structural degenerations are less aggressive than those observed in some other genetically-determined retinal degeneration mouse models such as rd1, rd4 and rd10 mice14,42,43 and may better resemble the course of RP in humans.