TGFB1 and diabetes mellitus: Comparison between groups shows the glomerulus and tubule of WT-DM increased significantly in TGF-β and Masson’s trichrome staining, indicating that the fibrosis level increased during STZ-induced diabetes, and Ktrans in the renal cortex and medulla was negatively correlated with fibrosis (shown in Figures S5a and S5b).