For example, Schmitz12 and Wright13 and their colleagues used BCL2 and BCL6 fusions, essential drivers of DLBCL pathogenesis, as classifier alterations, whereas Lacy et al.15 did not use them to classify their samples; on the other hand, Chapuy et al.14 used CNVs to define their clusters, which are especially relevant for the C2 subtype. Here, BCL2 is linked to diffuse large B-cell lymphoma.