DNAJC5 and malaria: The sole approved malaria vaccine, RTS,S/AS01, is a recombinant protein-based vaccine developed in 1987, which comprised a large portion of CSP (consisting of 19 NANP repeats and the C-terminal region) fused to the hepatitis B surface antigen (HBsAg) and co-expressed with wild-type (WT) HBsAg to form a particulate antigen, which displays this fragment of CSP at low valency9.