SVIP and frontotemporal dementia: In order to explore additional connections between SVIP and human disease, we screened a cohort of sporadic FTD patients (n = 341), with whole-genome sequencing data from the UCSF Memory and Aging Center (MAC), for putative pathogenic variants in SVIP. We found one potentially deleterious heterozygous nonsynonymous single nucleotide variant (SNV) in SVIP at genomic coordinates Chr11:22,844,669.