GESA analysis of the data from TCGA-CESC confirmed that HOXB4 inhibited the activity of the Wnt/β-catenin signaling pathway and correlation analysis showed that in cervical cancer, the expression of HOXB4, β-catenin, and c-myc genes were significantly negatively correlated (Supplementary Fig. 4). The gene discussed is HOXB4; the disease is cervical carcinoma.