HOXB4 and cervical cancer: In addition, the results showed that the IHC score for Ki67 staining was significantly decreased in the tumors stably overexpressing HOXB4, but markedly increased in the tumors with stable knockdown of HOXB4, compared with control tumors (Fig. 2h, i), demonstrating that HOXB4 suppressed tumorigenesis by inhibiting cervical cancer cell proliferation in vivo.