IP6K1 and cerebellar ataxia: We noticed that genetic variants, including SNPs and CNVs, at several of the novel loci have been found to be associated with other neuropsychiatric or neurodegeneration diseases, including variants in gene IP6K1 which are associated with general cognitive ability54, educational attainment55, and intelligence56; variants at the TRAF3 locus which are associated with brain imaging in SCZ at genome-wide marginal significance level57; and mutations in SPTBN2 that cause spinocerebellar ataxia with neurodegenerative feature58.