IFNA1 and infection: Of note, IFN-signaling was also the most strongly activated pathway in DC1s at the site of infection as assessed in bronchioalveolar lavage (BAL) samples (see Fig. 3E for reanalysis of public sincle-cell RNA sequencing [scRNA-seq] data of BAL immune cells of COVID-19 patients and controls, and SI Appendix, Fig. S1).