Wt mice could walk the balance beam without or with very few slips (1.235 ± 0.271, n = 28), whereas both Het (9.265 ± 1.079, n = 28, p < 0.0001) and Homo PKCγ-A24E (17.50 ± 0.056, n = 28, p < 0.0001) showed marked ataxia both at 3 and 6 months of age (Fig. 7A; Movies 1, 2, 3). The gene discussed is PRKCG; the disease is Ataxia.