To confirm the cytotoxic effects of inhibition of PDGFR and PKCα on BRCA1-deficient human breast cancer cells, we screened six widely used cell lines including two BRCA1 WT luminal lines, T47D and MCF7; two BRCA1 WT basal lines, MDA-MB231 and BT20; and two BRCA1 mutated lines, HCC1937 and SUM149. The gene discussed is PDGFRB; the disease is breast carcinoma.