TPO and Hepatic fibrosis: The BL TPO levels was also positively correlated with significant platelet count improvement in different genotype (genotype 1: P < 0.001; non-genotype 1: P = 0.016) and liver fibrosis severity (FIB-4 ≤ 3.25: P = 0.002; FIB-4 > 3.25: P = 0.001).