However, the level of lactate dehydrogenase (LDH) (474 vs 363, p < 0.001), blood urea nitrogen (BUN) (9.34 vs 5.77, p < 0.001), serum creatinine (SCr) (124 vs 65, p < 0.001) and serum cystatin C (1.09 vs 0.72, p < 0.001) were obviously higher in AKI group than non-AKI group. The gene discussed is CST3; the disease is acute kidney injury.