ADORA3 and idiopathic pulmonary arterial hypertension: We first demonstrated that the dysregulation of SAA1 (log2 FC = −1.57), CCR1 (log2 FC = −1.04), CXCR1 (log2 FC = −1.24), and ADORA3 (log2 FC = −1.03) may also play essential roles in the pathogenesis of IPAH.