PDGFR inhibition in GBM cell lines universally triggers a G2/M arrest [39] and in a PDGFRA/PDGFA driven glioblastoma mouse model chronic activation of PDGFRA facilitates microtubule dynamics during mitosis [40], suggesting a role for PDGFR in driving GBM cells towards mitosis. Here, PDGFA is linked to glioblastoma.