NFKB1 and diabetes mellitus: IL-10-induced TNF-α inhibition in these cells could be attributable to the destabilization of TNF-α mRNA expression via the suppression of p38 MAPK activation and the inhibition of NF-κB and RNA-binding Hu-antigen receptor (HuR) expression, all of which induce an inflammatory reaction and tissue injury during the course of diabetes and diabetic nephropathy.