Treatment with TGFβ [5 ng/mL] for 72 h induced transition of a cobblestone-like, epithelial to a fibroblastic or mesenchymal phenotype in control-treated but not in La-depleted cancer cells, as shown for A549 lung cancer cells (Figure 4A and Figure S3) and SCC22A head and neck cancer cells (Figure 4B). Here, TGFB1 is linked to cancer.