AON-ISE-AR-V7 suppresses prostate tumor cell survival by the inhibition of androgen receptor variant 7 mRNA synthesis [38], Nusinersen is an approved drug used for treating spinal muscular athropy [39], and IONIS-DGAT2RX ASO reduces DGAT2 enzyme production and is a potential treatment for nonalcoholic steatohepatitis [40,41]. The gene discussed is DGAT2; the disease is metabolic dysfunction-associated steatohepatitis.