A microarray study that investigated differences in the expression of genes associated with submucosal gland hyperplasia between healthy sinus mucosa and remodeled sinus mucosa of CRS patients revealed an increase in the expression of Dexmoglein 3 (DSG3) and Parathyroid hormone like hormone (PTHLH) in serous cells and Keratin 14 (KRT14) in myoepithelial cells of CRS mucosa [82]. The gene discussed is KRT14; the disease is congenital rubella syndrome.