Analyzing the significance of other growth factors by AS degrees, we found that FGF-2 as a specific and sensitive biomarker reached a fair level only in severe degree AS patients (fair level: AUC = 0.71, p = 0.04); VEGF-A—in mild degree AS patients (fair level: AUC = 0.70, p = 0.02); and FGF-21—in severe degree AS patients (fair level: AUC = 0.75, p = 0.02). The gene discussed is VEGFA; the disease is aortic stenosis.