In particular, in a model of streptozotocin (STZ)-induced hyperglycaemia, we found that increased ROS production is accompanied by an increased expression of the mitochondrial translocator protein (TSPO): a protein located at the level of the outer mitochondrial membrane [154,155,156] which has been found to be imbalanced in post-ischemic cardiac damage [157]. The gene discussed is TSPO; the disease is Hyperglycemia.