Exosomal cargo-lncRNA UCA1 mediated tamoxifen resistance [107] and lncRNA actin filament associated protein1 antisense RNA 1 (AFAP1-AS1) conferred trastuzumab resistance by binding to AU binding factor 1 and translating erythroblastic oncogene B2 (ERBB2) [106] in BC cells. The gene discussed is ERBB2; the disease is breast cancer.