TGFB1 and nephrosclerosis: These data are in keeping with our previous data showing that TGFβ1 induction of cardiofibroblasts into myofibroblasts and the parallel increase in matrix deposition could be inhibited using selective TG2 inhibitor 1–155, which when translated into mouse models of cardiac fibrosis and nephrosclerosis indicated that treatment with 1–155 caused a significant reduction of collagen deposition in these different animal models.