ACTA1 and idiopathic pulmonary fibrosis: Figure 7a and b show that both TG2-selective cell-permeable inhibitor 1–155 and cell-impermeable inhibitor R281 reduced TG2 expression in IPF fibroblast lysates, accompanied with significant decreased expression of FN and αSMA (Fig. 7a, c and d) and reduced TG2, FN and monomeric TGFβ1deposition in the ECM (Fig. 7e–h).