Conversely, hyperlipidemia results in the depletion of protective antioxidants, such as glutathione (GSH), and inhibits free radical scavenging enzymes, including catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) (Kang et al., 2014; Kohli et al., 1997). The gene discussed is CAT; the disease is hyperlipidemia.