Yao et al. reported that SERPINB1 ameliorates acute lung injury via dependent HO‐1‐oxidative stress (Wadsworth, Haines, Cornwell, Rodwell, & Paratz, 2012), demonstrating FoxO1/SERPINB1 ameliorates ROS production in diabetic nephropathy. Here, SERPINB1 is linked to diabetic kidney disease.