In in vitro study of mice, the effects of fisetin led to prohibition of metastasis and invasiveness, induction of the apoptosis, and regulation of the phosphatidylinositol‐3‐kinase/protein kinase B/mammalian target of rapamycin pathway, whereas suppression of growth of breast tumors and enhancement of tumor cell apoptosis were observed in serum of tumor‐bearing mice (Sun et al., 2018). The gene discussed is AKT1; the disease is neoplasm.