Moreover, talazoparib treatment also enhanced red only (RFP+ GFP−) punctae (i.e., autophagolysosomes) and yellow (RFP+ GFP+) punctae (i.e., autophagosomes) formation in mRFP-EGFP-LC3 expressing BECN1-KO breast cancer cells similar to that seen in control MCF-7 cells (Supplementary Fig. S5E, F). Here, MAP1LC3A is linked to breast carcinoma.