CBX4 and hepatocellular carcinoma: Because we reported that cytoplasmic CBX4 protein levels indicated poor survival for HCC patients who undergo surgical resection,10 CBX4 was followed by analysis of a TCGA data set and GTEx bioinformatics with 11 public HCC expression data sets that covered approximately 3401 clinical samples (Fig. S3 and Table S8).36 We clearly confirmed that a high CBX4 level contributes not only to tumorigenesis but also to a more advanced stage of HCC.