AKT1 and lung cancer: In lung cancer cells, a comparative genomic hybridisation (CGH) array identified DNA gain at 20q13 region, while fluorescence in situ hybridisation (FISH) analysis confirmed DNA copy number increase of EEF1A2.28 EEF1A2 enhanced Gefitinib resistance by preventing AKT phosphorylation for KRAS-mutated NSCLC.29 Li et al. showed that the DNA copy number, mRNA, and protein expression of EEF1A2 were increased in lung cancer cells using integrated omics analysis.