As a next step, we propose the prospective validation of ALG5 expression in a multi-centre cohort of patients undergoing maximal effort cytoreductive surgery in specialised centres for ovarian cancer surgery with established surgical quality as per objective criteria.18 Furthermore, the combination of gene expression and methylation profiling, and imaging-based approaches may lead to the establishment of a more robust prognostic model. Here, ALG5 is linked to ovarian cancer.