The results showed that granulosa cell lnc-GULP1–2:1 expression was significantly reduced in DOR patients as compared to normal patients (p < 0.05) (Fig. 1b), while lnc-GULP1–2:1 levels were significantly increased in PCOS patients when compared to those in normal patients (p < 0.05) (Fig. 1c). This evidence concerns the gene GULP1 and polycystic ovary syndrome.