CD4 and asthma: Similar correlation between proportion of paediatric patients with decreased CD3+, CD4+ and CD8+ T cells and severity of asthma exacerbation have shown Nguyen-Thi-Dieu et al. Author of this study observed that decrease of CD3+, CD4+, CD8+ T cells were associated with acute asthma exacerbation in children with asthma [33].