Also, variants in SOX6, a transcription factor shown to be involved in the promotion of adipogenesis (Iguchi et al. 2005; Leow et al. 2016), were previously related to obesity (Liu et al. 2009; Correa-Rodríguez et al. 2018). The gene discussed is SOX6; the disease is obesity due to melanocortin 4 receptor deficiency.