The analysis of the overlap between BMI and GWG associated loci in the ARIC cohort and T1DM cohort respectively showed enrichment in the TGFβ signaling pathway (GO:0071559, GO:0071560), regulation of stem cell differentiation (GO:1901532, GO:1902036, GO:0060218, GO:2000736) and polyol pathway (GO:0019751, GO:0046173). Here, TGFB1 is linked to type 1 diabetes mellitus.