The imprinting disorders of the 14q32.2 region in somatotroph adenomas compared with other subtypes were identified, and a high-resolution profile at 14q32.2 (chr14:100,487,787-101,563,452, including DLK1/MEG3 locus) is shown (Figure 3A). The gene discussed is DLK1; the disease is familial isolated pituitary adenoma.