The peculiarity of our patient relies on the association of lower motor neuron sufferance (confirmed by EMG) and cerebral calcification due to mutation in SLC20A2. Although we cannot exclude the co-occurrence of two different neurological diseases in the same patient, the presence of MN involvement and cerebral calcification may widen the clinical spectrum of PFBC patients. The gene discussed is SLC20A2; the disease is bilateral striopallidodentate calcinosis.