This included p66ShcA-deficient models of human luminal (MCF7), HER2-positive (HCC1954) and triple-negative (MDA-MB-468) breast cancer as well as p66ShcA-positive TNBC lines (Hs578T, MDA-MB-231, BT549, BT20) (Supplemental Figure 4A). Here, ERBB2 is linked to breast carcinoma.