Clearance of senescent cells has been shown to improve phenotypes in mouse models of Parkinson's disease (Chinta et al., 2018), tau‐dependent neurodegenerative diseases (Bussian et al., 2018; Musi et al., 2018), β‐amyloid‐related neurodegeneration (Zhang et al., 2019), and neuropsychiatric disorders (Ogrodnik et al., 2018). Here, MAPT is linked to neurodegenerative disease.