Previous studies have shown that the oncogene ETV1 (ETS variant 1 - member of the ETS family of transcription factors) contributes to neoplastic transformation of prostate cancer (25), breast cancer (26), esophageal adenocarcinoma (27), gastrointestinal stromal tumors (28), cranial germinomas (29), gastric cancer (30), melanoma brain metastases (31), and melanoma (32). The gene discussed is ETV1; the disease is esophageal adenocarcinoma.