ETV1 and melanoma: Previous studies have shown that the oncogene ETV1 (ETS variant 1 - member of the ETS family of transcription factors) contributes to neoplastic transformation of prostate cancer (25), breast cancer (26), esophageal adenocarcinoma (27), gastrointestinal stromal tumors (28), cranial germinomas (29), gastric cancer (30), melanoma brain metastases (31), and melanoma (32).