MACC1 and colorectal carcinoma: To validate the interactome screen, we performed immuno-precipitations (IP) of MACC1 in three CRC cell models: endogenously high MACC1 expressing SW620 cells and ectopic MACC1 overexpression in endogenously low MACC1 expressing SW480 cells (SW480/MACC1 and SW480/MACC1-GFP).