Zwaan CM et al. [17] found that t(9;11) samples from children with AML were more sensitive to a number of drugs than the other AML samples, and Ramakers-van Woerden et al. [18] reported significant differences in the drug sensitivity profile of MLL-rearranged samples from children with ALL compared with non-MLL-rearranged samples. The gene discussed is KMT2A; the disease is acute myeloid leukemia.