For example, TLR2 expression was up-regulated in human GC cell SGC7901, which was associated with Pam3CSK4 stimulation, indicating that TLR2 might be involved in the proliferation and metastasis of GC, indicating that TLR2 might serve as a novel therapeutic target against GC (Yang et al., 2014). The gene discussed is TLR2; the disease is gastric cancer.