The results of this study showed that in PBMCs undergoing a cytokine storm signal in rejection (Sarwal et al., 2003), with overlapping signatures of IFNG, CCL3, and TNF expression, along with TCR signaling also seen in the cytokine storm of COVID-19 (Chua et al., 2020; Ye et al., 2020), there is suppression of these inflammatory pathways after Tocilizumab treatment. This evidence concerns the gene CCL3 and COVID-19.