Thus, a low ratio of lncRNA KB-1980E6.3/IGF2BP1 was found under normoxia, and hypoxia-induced high level of lncRNA KB-1980E6.3 resulted in a high lncRNA KB-1980E6.3/IGF2BP1 ratio under hypoxia, which was reduced in accompany with lncRNA KB-1980E6.3 knockdown in hypoxic breast cancer cells (Fig. S7k). The gene discussed is IGF2BP1; the disease is breast carcinoma.