IGF2BP1 and neoplasm: To further confirm the stability of c-Myc mRNA is associated with lncRNA KB-1980E6.3 mediated IGF2BP1 recruitment under hypoxia conditions, we then performed a rescue experiment in lncRNA KB-1980E6.3 knockdown tumor cells and found that the decreased mRNA stabilities, mRNA and protein of c-Myc caused by lncRNA KB-1980E6.3 knockdown were partially restored by ectopic IGF2BP1 expression in hypoxic BT549 and Hs578T cells (Fig. S7e–h).