Consistent with these findings, our data showed that hypoxia-induced lncRNA KB-1980E6.3 primarily bound to the KH1/2 domain of IGF2BP1, leading to an increase in the binding ability of IGF2BP1 to m6A-modified c-Myc CRD mRNA and maintenance of c-Myc mRNA stability in breast cancer cells. Here, IGF2BP1 is linked to breast carcinoma.