ACTA2 and neoplasm: Compared with NE-4C cells, the tumor showed a general tendency of upregulation of a series of genes representing neural stemness (Fig. 2c), genes representing neuronal differentiation (Fig. 2d), and genes representing mesodermal (Acta2, T, Desmin, Kdr) and endodermal tissue (Afp, Foxa2) differentiation (Fig. 2e).