PHYH and cancer: In addition, decreased expression of PHYH correlated significantly with grade of cancer cells (G1-2 vs. G2-4, p = 0.025), the Union for International Cancer Control (UICC) stage (Stage I&II vs. Stage III&IV, p = 5.604e−05), and size of primary tumor (T1-2 vs. T3-4, p = 4.373e−05) (Fig. 2a–c, Table 1).