BRD2 and polycystic ovary syndrome: MI increases the sensitivity of polycystic ovaries to gonadotropins, leading to a reduction in the doses of FSH required:—500 IU for Lagana et al. [15],—327 IU for Zheng et al. [16] (p: 0.007); whereas the opposite is observed for DCI (Carlomagno paradox [17]).