Despite the negative regulatory effects of CDKN3 on CDK1 and CDK2, an oncogenic role for aberrant overexpression of CDKN3 has been implicated in numerous types of human cancer, including prostate cancer [37], gastric cancer [38], nasopharyngeal carcinoma [39], and esophageal cancer [40]. The gene discussed is CDKN3; the disease is gastric cancer.