IL-8 production in the HC-IPA + PTX group on days 1 and 3 after infection (60.82 ± 9.80 and 31.39 ± 19.08 ng/L, respectively) was significantly lower than that in the HC-IPA group (91.40 ± 5.68, 76.13 ± 13.82 ng/L, respectively, p < 0.05) (Fig. 4c). Here, CXCL8 is linked to infection.