MAK and neoplasm: These genes (HOX, S100 protein, ISPD, ATP13A4, MAK, and SLC7A8) were also significantly upregulated in tumor samples expressing BCOR K607E mutant as compared to that in tumor samples expressing wild-type BCOR (Fig. 5c and Figure S3B, Additional file 4), and these findings were consistent with gene expression profiling results obtained in cell lines.