A review by Curtin et al. proposes a clinical investigation of DNA-dependent PARP inhibitors against COVID-19 [4], highlighting that PARP1 and PARP2 actively increase and prolong inflammation and that the use of PARP inhibitors can limit this tissue damage, as well as decreasing the levels of proinflammatory cytokines [4]. The gene discussed is PARP1; the disease is COVID-19.