Nineteen people with T1D (7 females; age 35 ± 11 years; body mass index (BMI): 24.5 ± 2.7 kg/m2; HbA1c 7.3 ± 0.6% (56 ± 7 mmol/mol), diabetes duration 18 ± 11 years; 12 MDI/7 CSII; total daily insulin dose 41 ± 15 IU) were included in this analysis. The gene discussed is INS; the disease is type 1 diabetes mellitus.